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A method for detecting adverse drug reaction signals based on retrospective cohort study using electronic medical record
A method for detecting adverse drug reaction signals based on retrospective cohort study using electronic medical record
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机译：一种基于回顾性队列研究的电子病历检测药物不良反应信号的方法
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摘要
PURPOSE: retrospective population research is provided to increase the accuracy of result according to the electronic health record database of accumulation and supply different statistical result using electronic health record based on drug side-effect clue measuring method, to help additional determining user. ;CONSTITUTION: a drug can find side effect in this way and check which can find side effect, prompt to be determined (S100). A drug exposes and the Candidate Agents of non-exposed candidate are by from electronic health record database (S150). Non-exposed group of the exposure group of pharmaceutical composition a drug passes through the non-exposed candidate and important parameter of matching drug exposure candidate and drug. Medicament injects expression value and non-exposed is determined (S500) in the inspection result of medicine group patient in inspection result drug exposure group patient's medicament non-injection expression value. The toxic side effect of drug is to veritify infusion of medicine expression value and drug non-injection expression value (S600) by determining to count. ;The 2013 of copyright KIPO submissions;[Reference numerals] (AA) starts; (BB) terminate; (S100) determine test to detect drug side effect; (S150) drug exposure and non-exposed candidate set are extracted; (S200) side effect Check-up crowd is selected; (S250) one group of selection is not initially to the side effect of examinee; (S300) drug exposure and non-exposed candidate set are matched; (S500) after determining typical value (PostLab) injection,Drug and non-drug injection (NoLab) typical value; (S600) compare and determine that side effect occur in PostLab NoLab; (S700) coding 0 " or " 1 according to there is side effect; (S800) it statisticallys analyze, if any conditional logic regression analysis; (S900) drug of side effect is determined
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