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首页> 外文期刊>The Bulletin of Tokyo Dental College >Estimation of Optimal Amount of Fluoride Dentifrice for Adults to Prevent Caries by Comparison between Fluoride Uptake into Enamel In Vitro and Fluoride Concentration in Oral Fluid In Vivo
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Estimation of Optimal Amount of Fluoride Dentifrice for Adults to Prevent Caries by Comparison between Fluoride Uptake into Enamel In Vitro and Fluoride Concentration in Oral Fluid In Vivo

机译：通过比较牙釉质中氟的摄入量和口服液中氟的含量，估算成年人预防龋齿的最佳氟牙膏量

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摘要

Fluoride dentifrice has been accepted widely for use in caries prevention and its effectiveness has been confirmed. In order to enable the use of fluoride dentifrice effectively in daily brushing, the present study was performed to examine the relationship between fluoride uptake and the amount of fluoride dentifrice used and brushing time for adults. We examined the relationship between fluoride uptake into the surface layer (4-6 μm)of enamel and the active fluoride concentration in vitro and the relationship between the amount of fluoride dentifrice (1,000ppmF) used and the fluoride concentration in oral fluid in vivo. It became clear that fluoride uptake into the enamel was increased at the concentrations of 300ppmF or more. Fluoride uptake at 300ppmF was increased for 2min and became saturated thereafter. The results of the relationship between the fluoride concentration in the oral fluid and the amount of fluoride dentifrice used indicated that the amount of dentifrice that could maintain the mean fluoride concentration at 300ppm or more for 2min was 1.0g or more. From these results, the recommended amount of fluoride dentifrice (1,000ppmF) is 1.0g or more for adults.
机译：氟化物洁齿剂已广泛用于预防龋齿，其有效性已得到证实。为了使氟化物洁齿剂能够有效地用于日常刷牙，本研究旨在检查成人的氟化物摄取量与所用氟化物洁齿剂的用量和刷牙时间之间的关系。我们检查了氟在牙釉质表层（4-6μm）中的摄取与体外活性氟化物浓度之间的关系，以及体内使用的氟化洁牙剂（1,000ppmF）的量与口腔液中氟化物浓度之间的关系。显然，在300ppmF或更高的浓度下，搪瓷中氟的吸收量增加了。 300ppmF的氟化物吸收增加2分钟，然后变为饱和状态。口腔液中的氟化物浓度与所使用的氟化物洁牙剂的量之间的关系的结果表明，能够使平均氟化物浓度维持在300ppm以上且持续2分钟的洁牙剂的量为1.0g以上。根据这些结果，成人的氟化物洁牙剂的推荐量（1,000ppmF）为1.0g或更高。

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