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首页> 中文期刊> 《海南医科大学学报(英文版)》 >Effects of different anesthesia depth on the level of plasma cortisol during operation and the score of postoperative MMSE in elderly patients with radical operation for gastric carcinoma

Effects of different anesthesia depth on the level of plasma cortisol during operation and the score of postoperative MMSE in elderly patients with radical operation for gastric carcinoma

     
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摘要

Objective:To observe the effects of different anesthesia depths on the level of plasma cortisol during operation and the score of postoperative MMSE in elderly patients underwent radical gastrectomy.Methods: A total of eighty seven elderly patients undergoing radical gastrectomy were enrolled in this study. Continuous infusion of propofol and remifentanil for anesthesia and maintenance of propofol were divided into two groups: BIS-I (BIS: 45-55) and BIS-II (BIS: 55-65) by adusting the doses of propofol. The data were recorded as following, thewhole dosage of propofol, the time of extubation and the score of VAS. The level of plasma cortisol was finished at the time of incision and tracheal intubation. MMSE scores were recorded on the day before operation and follow-up at 3 and 7 d postoperatively. Record the patient''s operation to discharge time, postoperative complications.Results: The concentration of cortisol in BIS-I group was higher than that in BIS-II group. There was no significant difference in extubation time, extubation VAS score and MMSE score after operation.Conclusion:There were no significant differences in the BIS values between 45 and 65 for the elderly patients undergoing upper abdominal surgery, and there were no significant differences in the patients'' postoperative stress, wake, extubation, early postoperative pain scores and postoperative cognitive function. BIS values in 45-55 compared to 55-65 patients with low plasma cortisol levels may be associated with better control of stress levels, to maintain the BIS value between 45-55 anesthesia depths is more reasonable.

著录项

  • 来源
    《海南医科大学学报(英文版)》 |2017年第9期|P.143-146|共4页
  • 作者

    Duo-Zhi Wu; Hai Xie; Jian Liu; Jing Du; Tie-Jun Li; Jian-Jun Ren; Zhen-Ming Dong;

  • 作者单位

    [1]Department of Anesthesiology;

    Hainan General Hospital;

    Haikou570311;

    China;

    [2]Department of Anesthesiology;

    The First Affiliated Hospital of Hainan Medical College;

    Haikou570102;

    China;

    [3]Department of Anesthesiology;

    Nanjing General Hospital;

    Nanjing210002;

    China;

    [2]Department of Anesthesiology;

    The First Affiliated Hospital of Hainan Medical College;

    Haikou570102;

    China;

    [1]Department of Anesthesiology;

    Hainan General Hospital;

    Haikou570311;

    China;

    [4]Department of Anesthesiology;

    The Second Hospital of Hebei Medical University;

    Shijiazhuang050000;

    China;

    [4]Department of Anesthesiology;

    The Second Hospital of Hebei Medical University;

    Shijiazhuang050000;

    China;

  • 原文格式 PDF
  • 正文语种 CHI
  • 中图分类 肿瘤学;
  • 关键词

    Old age; Total intravenous anesthesia; Anesthesia depth; MMSE score; Bispectral index; Plasma cortisol;

    机译：老年;全静脉麻醉;麻醉深度;MMSE评分;双光谱指数;血浆皮质醇;
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